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Dev121723 1390..1395

Lysophosphatidic acid (LPA) is a bioactive phospholipid that is present in all tissues examined to date. LPA signals extracellularly via cognate G protein-coupled receptors to mediate cellular processes such as survival, proliferation, differentiation, migration, adhesion and morphology. These LPA-influenced processes impact many aspects of organismaldevelopment. Inparticular, LPAsignallinghasb...

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Biol. Pharm. Bull. 30(8) 1390—1394 (2007)

earth’s crust and has been implicated as an etiologic factor in neurological disorders including Alzheimer’s disease, Parkinson’s dementia syndrome, and dialysis encephalopathy syndrome. In fact, some evidence supports the selective accumulation of Al within neurons containing neurofibrillay tangles in patients with Alzheimer’s disease and within the aging human brain. Meiri et al., have also r...

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volume 3  issue 10

pages  1- 205

publication date 2011-06-22

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